Very few enemies will afflict your party with Bleed or Blight damage, and there are no curios that require either of these provisions.

Bandages or Antivenom - Even less important are the Bandages and Antivenom.It isn't overly important to bring them with you. Medicinal Herbs - These have a small use in the Ruins - cleansing the Iron Maiden and Alchemy Table.Locked curios, like the Sarcophagus or Display Cabinet, can reward you with gold, heirlooms, and trinkets. Skeleton Keys - Also very valuable, as there are a few curious that can only be unlocked by using a Skeleton Key.Bring at least three Holy Water for a short run, stacking up more if you're heading in for a longer expedition. Loads of the curios, like the Confession Booth, Decorative Urn, and the Holy Fountain, can only be interacted with if you packed enough Holy Water. Holy Water - Holy Water is essential in the Ruins.They can be the make or break of getting out alive.

Provisions are the items that you can take with you into a run.

Darkest dungeon ruins medium provisions